Performance Medicine
Clinical science meets
human performance.
Written by a physician who actually trains. Not wellness content. Not gym-bro advice. The clinical science behind how you perform, recover, and age — for people who refuse to do it quietly.
What I Write About
Five pillars. One gap to close.
The Metrics That Actually Matter
VO2 max, grip strength, fasting insulin, visceral fat, lactate threshold. Not cholesterol and BMI.
Training Mistakes Your Doctor Would Never Catch
Overtraining, rhabdomyolysis, zone 2 deficiency, sarcopenia. The clinical-athletic overlap.
What the Data Says vs. What You're Doing
Exercise science translated without dumbing it down. Periodization, zone 2, programming for executives.
The Long Game
Functional capacity at 75 as the target. Not aesthetics. Not lab values. Performance-based longevity.
Field Notes
Personal data, training logs, real experiments. VO2 max progression, DEXA over time, real numbers on the table.
Who's Behind This
Andrew Irwin, MD
Internal medicine physician and Certified Strength and Conditioning Specialist with two decades of competitive training across Ironman triathlons, marathons, Hyrox, rugby, and competitive hockey.
I've delivered medicine in remote Himalayan villages with no internet and no backup. I've admitted patients whose bodies weren't strong enough to tolerate life-sustaining treatments. I've watched the trajectory play out — athletic in youth, busy in middle age, debilitated by 60.
It doesn't have to go that way.
The newsletter for people who refuse to age quietly.
Clinical science meets human performance. Delivered to your inbox. Written by a physician who actually trains.
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